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Evaluation of effects of rapid infusion of normal saline during vessel anastomosis on graft function and acid base balance in kidney transplantation surgery

Not Applicable
Conditions
Chronic kidney disease, stage 5.
Chronic uraemia End stage kidney disease: in allograft failure NOS on dialysis without dialysis or transplant
Registration Number
IRCT2014041516415N1
Lead Sponsor
Department of Transplantation of St Alzahra Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

age between 18-65 years old; end stage renal disease; candidate of elective live donor kidney transplantation; no previous kidney transplantation; no liver disease; ejection fraction more than 45%; ASA I and II
Exclusion criteria: Bleeding more than 3 ml/kg; vascular anomaly in donor kidney

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Anion Gap. Timepoint: Before and after fluid infusion. Method of measurement: Calculation of anion gap by measuring blood gas analysis and and blood electrolytes concentration.
Secondary Outcome Measures
NameTimeMethod
Electrolyte concentration, urine output, blood creatinine concentration. Timepoint: Before and after fluid infusion, 24 and 48 hours after surgery. Method of measurement: Blood sampling and urine collection.
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