Acute Cardiovascular Responses to a Single Exercise Session in Patients With Post-COVID-19 Syndrome

Not Applicable

Recruiting

Brief Summary: The objective of the study is to compare the acute cardiorespiratory and perceptual responses to a physical exercise session in those infected by Covid-19 with and without persistent symptoms.

Detailed Description: The study will be a crossover carried out in two groups (with and without persistent symptoms of Covid-19). Participants in both groups will undergo a control session and an exercise session and cardiorespiratory and perceptual responses will be obtained before, during and after the sessions. In the exercise session, participants will perform aerobic exercises, strength exercises and muscle stretching, while in the control session participants will remain seated. Blood pressure, heart rate, cardiac autonomic modulation, peripheral oxygen saturation, vascular function and perception of affect will be obtained.

Recruitment & Eligibility

Inclusion Criteria

Post-Covid Syndrome group:

have had a positive RT-PCR test for Covid-19;
present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
have the cognitive and physical capacity to perform the exercises; It is
low cardiovascular risk classification according to the American College of Sports Medicine criteria.

Healthy group:

not present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
have the cognitive and physical capacity to perform the exercises; It is
low cardiovascular risk classification according to the American College of Sports Medicine criteria.

Exclusion Criteria

Not provided

Arm && Interventions

Group	Intervention	Description
Exercise	Control session	In the exercise session, participants will perform aerobic, free active and flexibility exercises and will last approximately 45 minutes.
Exercise	Exercise session	In the exercise session, participants will perform aerobic, free active and flexibility exercises and will last approximately 45 minutes.
Control	Exercise session	In the control session, participants will remain seated for 60 minutes.
Control	Control session	In the control session, participants will remain seated for 60 minutes.

Primary Outcome Measures

Name	Time	Method
Change in Blood pressure	Before and 30 and 50 minutes after the end of the exercise and control interventions	Assessment of the systolic and diastolic blood pressure using an automatic device
Change in Heart rate variability	Before and 30 and 50 minutes after the end of the exercise and control interventions	Assessment of the heart rate variability indicators using a heart rate monitor
Change in flow mediated dilation	Before and 30 minutes after the end of the exercise and control interventions	Assessment of the flow mediated dilation using a doppler ultrasound
Change in peak exhalation flow	Before and 5 minutes after the end of the exercise and control interventions	Assessment of the peak exhalation flow using a peak flow device
Change in oxygen saturation	Before, during and 5 minutes after the end of the exercise and control interventions	Assessment of the peripheral oxygen saturation using a pulse oximeter

Secondary Outcome Measures

Name	Time	Method
Change in heart rate	Before and continuously during exercise and control interventions	Assessment of heart rate using a heart rate monitor
Change in affective response	Before and every 5 minutes during exercise and control interventions	Assessment of affective response using a felling scale

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