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The effect of additional use of remimazolam and flumazenil on the recovery of anesthesia in propofol based total intravenous anesthesia for dental treatment in mentally disabled outpatients

Not Applicable
Completed
Conditions
Factors influencing health status and contact with health services
Registration Number
KCT0007794
Lead Sponsor
Seoul National University Dental Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
54
Inclusion Criteria

1. Adult mentally disabled patients who were expected to undergo dental treatment under general anesthesia at the National Dental Care Center for Persons with Special Needs at Seoul National University Dental Hospital
2. American Society of Anesthesiologists (ASA)physical classification II-III
3. The patient understands the procedure for participating in a clinical trial, and consent can be provided in writing or, if the patient is unable, a legal representative can sign for it

Exclusion Criteria

1. American Society of Anesthesiologists (ASA)physical classification IV-V
2.BMI > 35kg/m^2
3. Allergies to anesthetic or analgesic medications (propofol, remifentanil, remimazolam, rocuronium bromide, sugammadex, flumazenil)
4. Patients who receive the following medications within 24 hours prior to general anesthetics: anxiolytics, antipsychotics, rifampicin, succinycholine, neostigmine, flumazenil, cyclosporin
5. Patients with tracheostomy
6. Previous participant within 6 month
7. anticipated within 1hour surgery

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
length of Difference of anesthetic care unit stay [ Time Frame: immediately after discharge from the post-anesthetic care unit ] length of post-anesthetic care unit stay (minute)
Secondary Outcome Measures
NameTimeMethod
time of eye opening;time of extubation;Modified Aldrete score within 5 minutes of arrival at the post-anesthetic care unit;postoperative quality of recovery score-15;Incidence of postoperative nausea and vomiting during the first 24 hours postoperatively
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