EUCTR2010-019513-24-GB
Active, not recruiting
Phase 1
Antibiotics for exacerbations of chronic obstructive pulmonary disease: a pilot randomised trial within the General Practice Research Database - Antibiotics for exacerbations of chronic obstructive pulmonary disease
ondon School of Hygiene & Tropical Medicine0 sites150 target enrollmentJune 7, 2010
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Diagnosed at a GP visit as suffering from acute exacerbation of COPD a.Medical history of COPD b.Increase in dyspnoea AND increase of (non-purulent) sputum volume
- Sponsor
- ondon School of Hygiene & Tropical Medicine
- Enrollment
- 150
- Status
- Active, not recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Study inclusion criteria
- •(i)Age 40 years or older
- •ii)Diagnosed at a GP visit as suffering from acute exacerbation of COPD
- •a.Medical history of COPD
- •b.Increase in dyspnoea and sputum volume
- •c.Sputum that is non\-purulent
- •iii)Able and willing to provide informed consent to study participation
- •iv) Subjects who in the opinion of the GP Investigator could be prescribed an antibiotic
- •Study exclusion criteria
- •(i)COPD exacerbation in the last 28 days
Exclusion Criteria
- •(i)Purulent sputum (as determined by GP)
- •(ii)COPD exacerbation in the last 28 days
- •(iii)Immediate referral to specialist care for treatment of COPD exacerbation
- •(iv)Prescribed an antibiotic in the previous 3 months
- •(v)Contra\-indication to antibiotics. Further details can be found in the British National Formulary (section 5\)
Outcomes
Primary Outcomes
Not specified
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