ISRCTN72035428
Completed
未知
Antibiotics for Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD): a pilot randomised trial within the General Practice Research Database (GPRD)
ondon School of Hygiene and Tropical Medicine (LSHTM) (UK)0 sites150 target enrollmentMarch 15, 2010
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Chronic obstructive pulmonary disease
- Sponsor
- ondon School of Hygiene and Tropical Medicine (LSHTM) (UK)
- Enrollment
- 150
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Aged 40 years or older, either sex
- •2\. Diagnosed at a GP visit as suffering from acute exacerbation of COPD:
- •2\.1\. Medical history of COPD
- •2\.2\. Increase in dyspnoea and increase of (non\-purulent) sputum volume
- •3\. Able and willing to provide informed consent to study participation
- •4\. Fully registered with the general practice for at least 6 months (i.e. subjects who are newly registered with the practice will not be eligible)
- •5\. Subjects who had not been prescribed an antibiotic in the previous 3 months
- •6\. Subjects who in the opinion of the GP Investigator could be prescribed an antibiotic
Exclusion Criteria
- •1\. Purulent sputum (as determined by GP)
- •2\. COPD exacerbation in the last 28 days
- •3\. Immediate referral to specialist care for treatment of COPD exacerbation
- •4\. Prescribed an antibiotic in the previous 3 months
- •5\. Contra\-indication to antibiotics. Further details can be found in the British National Formulary (section 5\).
Outcomes
Primary Outcomes
Not specified
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