Perioperative decongestion and hemostasis, and postoperative analgesia for FESS after intranasal application of cocaine, tetracaine-oxymetazoline or ropivacaine-oxymetazoline

Not yet recruiting

• Conditions: nasal polyposis; swollen mucous membrane of the nose; 10046304; 10038737

• Registration Number: NL-OMON32081
• Lead Sponsor: Canisius Wilhelmina Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

First FESS-operation
Age: >=18years
ASA 1-3 (patient classification as by the American Society of Anesthesiology)
Competent and the Dutch language understanding in word and reading

Exclusion Criteria

Perioperative intake anticoagulants
Chronic painsyndrom
Pregnancy
Allergy for lokal anesthetics
Psychiatric disorder with disease of reality experience

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The surgeon will range the operative site for decongestion and hemostasis using<br /><br>a numeric rating scale (NRS 0-10).<br /><br><br /><br>The perooperative bloodloss, the amount of extra ultracaine-epinefrine<br /><br>injections and the operation-time will be noted<br /><br><br /><br>Pain (+medication) nausea/vomiting (+medication), heartrate and bloodpressure,<br /><br>drowsiness and bloodloss will be registrated till 24 hours postoperatively<br /><br>(t=0,1 2, 6, 12, 18 and 24h)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Satisfaction of the patient about the treatment<br /><br>Complications</p><br>