Feasibility of Dexmedetomidine in Children With Respiratory Morbidities Undergoing Deep Sedation for Magnetic Resonance Imaging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- the occurrence of successful sedation
研究概览
简要总结
This study aimed to determine the feasibility of dexmedetomidine in children with respiratory morbidities who required deep sedation for magnetic resonance imaging (MRI) scans.
详细描述
Electronic medical records of children with at least 3 characteristics of respiratory morbidities were retrospectively reviewed. All study patients received dexmedetomidine bolus over 10 min followed by a continuous infusion to achieve a minimum Ramsay Sedation Score of 5. Patients were monitored for hemodynamics, total dose of dexmedetomidine received, adverse events experienced and sedation characteristics.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Month 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children up to the age of 16 years with at least 3 characteristics of respiratory morbidities
排除标准
- •Children who had an American Society of Anaesthesiologists (ASA) physical status classification IV
- •Documented pre-existing cardiac conduction abnormalities
- •Renal impairment
结局指标
主要结局
the occurrence of successful sedation
时间窗: 1 hour
completion of imaging without requirement for rescheduling or general anaesthesia, and in the absence of adverse respiratory events such as apnoea, cough, oxygen desaturation, and bronchospasm or unplanned escalation of care (e.g. transfer from ward to paediatric intensive care unit or prolonged hospitalization).
次要结局
- the presence of nausea and vomiting.(4 hours)
- the presence of bradycardia(4 hours)
- the presence of hypertension(4 hours)
研究者
Veerle Van Mossevelde
Data Nurse
Universitair Ziekenhuis Brussel