Monitoring Recurrence of Individual tumor by serial Observation of Known gene Alterations
Not Applicable
Recruiting
- Conditions
- Pan-cancer (approximately 20 types of origins)Pan-cancer, malignancy
- Registration Number
- JPRN-jRCT1020190017
- Lead Sponsor
- ishizuka Satoshi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
>Diagnosis of malignancy. Histologic diagnosis is preferred but not mandatory.
>Intention to treat for volume reduction or growth suppression of the tumor. Cases receive secondary treatment are eligible. Cases with nodes or organ metastasis are accepted.
>Estimated life expectancy is longer than 180 days.
>Stages estimated having approximately 30% recurrence rate.
>Pre-treatment blood sample is available.
Exclusion Criteria
>Treatment has initiated without pre-treatment blood sample.
>Pregnancy.
>Periodical survey is difficult due to location or financial reasons.
>Any other ineligible reasons.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression-free survival
- Secondary Outcome Measures
Name Time Method >Proportion of cases whose ctDNA changes according to tumor burden<br>>Proportion of cases whose ctDNA changes while tumor burden changes