Hypertonic saline and Salbutamol in children who get admitted with mild to moderate exacerbation of asthma
Phase 3
- Conditions
- Health Condition 1: J452- Mild intermittent asthma
- Registration Number
- CTRI/2023/10/058421
- Lead Sponsor
- SHIVARAMAN P
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children with clinically diagnosed Asthma aged 6 years - 18 years presenting to pediatric OPD , Pediatric chest clinic with mild/moderate exacerbation as assessed by PRAM score
Exclusion Criteria
Pre-existing chest wall/ neuromuscular disease/ other pulmonary conditions such as
CF, ILD, Bronchiectasis, PCD, etc.
Children who received a short acting beta-2 agonist within 6 hrs
Children who received a long-acting beta-2 agonist within 12 hrs
Children not able to perform Spirometry.
Children involved in any other trial.
Repeated admissions
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FEV1 measured before and at <br/ ><br>60 minutes after nebulization.Timepoint: 0,20,40 and 60 minutes
- Secondary Outcome Measures
Name Time Method Clinical severity score (PRAM) measured at baseline and at 60 minutes after nebulization.Timepoint: 0,20,40 and 60 minutes;Other Spirometry parameters <br/ ><br>(PEFR; MMER) measured at baseline and at 60 minutes.Timepoint: 0,20,40 and 60 minutes