The effect of nebulised salbutamol and isotonic saline on exercise induced bronchoconsonstriction in elite skaters following a 1500 meter race.
- Conditions
- Elite skaters perform in cold air, an environment which has a low absolute humidity. In training and during competition, when the level of exertion is high, the skater repeatedly breathes cold and dry air, resulting in an inflammation of the lungs similar to that seen in asthma. This inflammation may cause bronchus obstruction after exercise. In order to combat the consequences of performing in dry or unconditioned air, this research makes use of a fully portable ultrasonic nebulizer (OMRON).
- Registration Number
- NL-OMON26511
- Lead Sponsor
- drs. J.M.M. DriessenThialfweg 418441 PW Heerenveen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 41
Inclusion Criteria
1. Age between 18 and 35 years;
2. Elite speedskater;
Exclusion Criteria
1. Ultrasonic nebulization with tap water or saline solutions within 48 hours before testing;
2. FEV1 <70%;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect on the decrease in FEV1 after exercise by ultrasonic nebulization with salbutamol 1 mg or 0.9% sodium chloride (NaCl) (Carlson, et al, 2008, Carlson, et al, 2008) compared to controls with no intervention.
- Secondary Outcome Measures
Name Time Method 1. Analyze the change in airway resistance after exercise, measured with the FOT and the effect of salbutamol on this change compared to, 0.9% NaCl and controls;<br /><br>2. Analyzing the change in respiratory reactance after exercise, measured with the FOT and the effect of salbutamol on this change compared to 0.9% NaCl and controls;<br /><br>3. Analyzing the change in electro physiological activity of the respiratory muscle system, measured with EMG with salbutamol on this change compared to , 0.9% NaCl and controls.