Resistive Training in Coronariopathy with Diastolic Dysfunctio

Not Applicable

Not yet recruiting

• Conditions: Heart Failure; Left Ventricular Failure; I50.1

• Registration Number: RBR-8rgwcq
• Lead Sponsor: Hospital Universitário Maria Rosa Pedrossian

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients of both sexes; Age between 35 and 75 years old; Patients with chronic coronary artery disease by clinical and angiographic criteria, in different degrees of diastolic dysfunction by echocardiographic criteria; Patients who are stable for more than 30 days of symptoms, in regular use of prescription drugs; Patients with HFPEF (LVEF higher than 50%) or HFREF (Ejection Fraction between 30% and 50%);Assessed patients should be able to perform transthoracic doppler echocardiography, inspiratory muscle assessment, peripheral vascular doppler, treadmill exercise cardiopulmonary exercise testing, and to respond to the Minnesota quality of life questionnaire voluntarily before and after the experimental intervention

Exclusion Criteria

HF patients and EF lower than 30%; HF patients and EF higher than 30% in Functional Class IV; Recent myocardial infarction (less than 30 days), unstable angina (more than 30 days) or sustained complex ventricular arrhythmia; Severe valvulopathies with surgical indication; Uncontrolled SAH: systolic BP higher than 190 mmHg or diastolic BP higher than 120 mmHg;
Inability to exercise on a treadmill due to severe neuromuscular, neurological, orthopedic or psychological limitation; Patients without echocardiographic criteria of diastolic dysfunction by either pulsed or tissue Doppler; Patients with nonobstructive coronary insufficiency or nonatherosclerotic coronary heart disease

Study & Design

• Study Type: Intervention
• Study Design: Not specified