Progressive Resistive Training combined with Inspiratory Muscle Training in Coronariopathy with Diastolic Dysfunction: Clinico-functional cardiovascular outcomes

Hospital Universitário Maria Rosa Pedrossian0 个研究点开始时间: 2019年11月21日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Patients of both sexes; Age between 35 and 75 years old; Patients with chronic coronary artery disease by clinical and angiographic criteria, in different degrees of diastolic dysfunction by echocardiographic criteria; Patients who are stable for more than 30 days of symptoms, in regular use of prescription drugs; Patients with HFPEF (LVEF higher than 50%) or HFREF (Ejection Fraction between 30% and 50%);Assessed patients should be able to perform transthoracic doppler echocardiography, inspiratory muscle assessment, peripheral vascular doppler, treadmill exercise cardiopulmonary exercise testing, and to respond to the Minnesota quality of life questionnaire voluntarily before and after the experimental intervention

•HF patients and EF lower than 30%; HF patients and EF higher than 30% in Functional Class IV; Recent myocardial infarction (less than 30 days), unstable angina (more than 30 days) or sustained complex ventricular arrhythmia; Severe valvulopathies with surgical indication; Uncontrolled SAH: systolic BP higher than 190 mmHg or diastolic BP higher than 120 mmHg;
•Inability to exercise on a treadmill due to severe neuromuscular, neurological, orthopedic or psychological limitation; Patients without echocardiographic criteria of diastolic dysfunction by either pulsed or tissue Doppler; Patients with nonobstructive coronary insufficiency or nonatherosclerotic coronary heart disease

发起方

Hospital Universitário Maria Rosa Pedrossian