Visual and Electromyography Assessments in Response to Train-of-Four Stimulation of the Ulnar Nerve

Not Applicable

Completed

Brief Summary: Researchers are comparing the accuracy of measuring muscle relaxation during and after surgery with a device that provides numeric value versus visual observation to count of muscle twitches or absence of them by a medical provider monitoring your anesthesia during surgery.

Recruitment & Eligibility

Inclusion Criteria

Age > or = 18 years old
Patients willing to participate and provide an informed consent
Patients undergoing an elective surgical procedure that requires use of NMBA agents administered intraoperatively.

Exclusion Criteria

Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
Patients having surgery that would involve prepping the arm or leg into the sterile field

Arm && Interventions

Group	Intervention	Description
Non-dominant hand	TetraGraph	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the non-dominant hand and routine clinical monitor on dominant hand
Dominant hand	TetraGraph	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the dominant hand and routine clinical monitor on non-dominant hand

Primary Outcome Measures

Name	Time	Method
Subjective Evaluation to Neurostimulation	up to 1 hour postoperatively	The percentage of subjective evaluations that overestimated the response of the adductor pollicis muscle following neurostimulation of the ulnar nerve when compared to objective measurements.

Secondary Outcome Measures

Name	Time	Method
Incidence of Residual Neuromuscular Blockade	Up to 1 hour postoperatively	Number of subjects with train of four ratio \< 0.9 after administration of reversal agent.