Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting

Not Applicable

Completed

Brief Summary: Researchers are comparing the ease of use and repeatability of the force vs electrical activity produced by a muscle after it has undergone nerve stimulation during a surgical procedure in which the patients' arm movement is restricted (placed under surgical drapes) in laparoscopic or robotic procedures.

Recruitment & Eligibility

Inclusion Criteria

Age > or = 18 years old
Patients willing to participate and provide an informed consent
Patients undergoing an elective laparoscopic or robotic surgical procedure that requires use of NMBA agents administered intraoperatively.

Exclusion Criteria

Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
Patients having surgery that would involve prepping the arm or leg into the sterile field

Arm && Interventions

Group	Intervention	Description
Dominant hand	Tetragraph	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the dominant hand, ToFscan placed on non-dominant hand
Dominant hand	ToFscan	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the dominant hand, ToFscan placed on non-dominant hand
Non-dominant hand	Tetragraph	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the non-dominant hand, ToFscan placed on dominant hand
Non-dominant hand	ToFscan	Subject scheduled to undergo an elective surgical procedure will have TetraGraph device lead placement on the non-dominant hand, ToFscan placed on dominant hand

Primary Outcome Measures

Name	Time	Method
Accuracy of Values Between Tetragraph and ToFscan	Up to 1 hour postoperatively	The number of subject's who's residual neuromuscular blockage units are the same on both the TetraGraph and the ToFscan

Secondary Outcome Measures

Name	Time	Method
Incidence of Residual Neuromuscular Blockade	Up to 1 hour postoperatively	Number of patients with train of four ratio \< 0.9 after administration of reversal agent.

Locations (3): Mayo Clinic in Florida
🇺🇸
Jacksonville, Florida, United States
Université de Lorraine, CHU de Brabois
🇫🇷
Vandœuvre-lès-Nancy, France
University of Debrecen
🇭🇺
Debrecen, Hungary
Mayo Clinic in Florida
🇺🇸Jacksonville, Florida, United States