The effect of inhaled salbutamol on treatment of Transient tachypnoea of newbor

Phase 3

Recruiting

• Conditions: Transient tachypnoea of newborn.; Transient tachypnea of newborn; P22.1

• Registration Number: IRCT20190328043133N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Consent of the infant's parents to participate in the study
Minimum gestational age of 35 weeks
Diagnosis of TTN is based on the criteria of respiratory distress less than 6 hours after birth (respiration rate more than 60 breaths per minute, grunting, nasal flaring or retraction, cyanosis) and known findings on X-ray (fluid in minor fissures, hyperventilation , prominent central vascular markings, flattening of the diaphragm, increased anterior-posterior diameter, bilateral perihilar congestion).
Weight more than 2 kg

Exclusion Criteria

Meconium aspiration
Other known causes of tachypnea in infants such as (RDS, PPHN, pneumonia, meconium aspiration, premature sepsis of infants, polycythemia, hypocalcemia, hypoglycemia)
Abnormal auscultation (Murmur) during cardiac examination
Tachycardia (number of heart rate more than 180 per minute) or arrhythmia
Asphyxia
Incidence of drug drug reactions(tremor, hypoglycemia, hypokalemia, increase in blood pressure, tachycardia and arrhythmia)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tachypnea duration. Timepoint: Before the intervention, 30 minutes, 60 minutes and 4 hours after the intervention. Method of measurement: using a watch.