Effect of local application of Glycyrrhiza glabra and eucalyptus extract for the prevention of Mucositis

Phase 3

• Conditions: Oral Mucositis.; Stomatitis and related lesions

• Registration Number: IRCT20190415043279N4
• Lead Sponsor: Sanandaj University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 July 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Head and neck carcinoma
Full awareness
Oral mucosal health

Exclusion Criteria

History of allergy to medicinal plants
High blood pressure
Diabetes
Autoimmune diseases
Cardiovascular disease
Neutropenia
The presence of mucosal lesions in the mouth
Previous history of radiotherapy and chemotherapy
Chronic liver diseases
Active collagen vascular disease
Non-use of drugs; alcohol; cigarettes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of oral mucositis. Timepoint: The beginning of the intervention, every week continuously, the end of the intervention, one week after the end of the intervention. Method of measurement: Clinical examination by the dentists and filling standardized physician judged mucositis grading forms.;The need for painkillers during the course of treatment. Timepoint: During the course of treatment. Method of measurement: Check list.;Need for intravenous nutrition during the course of treatment. Timepoint: During the course of treatment. Method of measurement: Check list.;Weight loss during the course of treatment. Timepoint: During the course of treatment. Method of measurement: Check list.