to achieve maximum anaesthetic success using ketorolac and pregabalin premedication with 1.7mL of articaine using Inferioor alveolar block with infiltration in symptomatic teeth

Not yet recruiting

• Conditions: irreversible pulpitis

• Registration Number: CTRI/2020/02/023261
• Lead Sponsor: dr suruchi agrawal

Brief Summary

This is a prospective, randomized, controlled, double blind study will be to achieve maximum anaesthetic success using ketorolac and pregabalin premedication with 1.7mL of articaine IANB with BI in teeth with symptomatic IP. Sample size of this trial is 150 which is divided into three groups of 50 each. All patients will be asked to rate the pain on the HP VAS to analyse the level of pain during access opening and after instrumentation.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-01-29
• Study Start: 2020-02-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• 1 Symptomatic irreversible pulpitis 2 Patients with active pain in a mandibular first or/and second molar, 3 Patients in good health, with no previous history of allergy to any kind of local anesthesia, sulphites or other drugs that would alter pain perception.
• 4 Prolonged response to cold testing with Endo-frost (Roeko Langenace, Germany) 5 Absence of any periapical radiolucency on periapical radiographs 6 A vital coronal pulp on access opening.

Exclusion Criteria

1 Subjects younger than 18 years and older than 60 2 History of significant medical problems 3 Taken central nervous system depressants or any analgesic medication within 8 hours 4 Pregnancy 5 Allergy to articaine, ketorolac, pregabalin 6 Unable to give informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
compare the effect of oral premedication with ketorolac and pregabalin on anesthetic efficacy of inferior alveolar nerve block and buccal infiltration in symptomatic patients with irreversible pulpitis	pain assessment done at 15 minutes

Trial Locations

Locations (1)

SGT Dental College; 🇮🇳 Gurgaon, HARYANA, India

SGT Dental College

🇮🇳Gurgaon, HARYANA, India

Dr Suruchi Agrawal

Principal investigator

8955997107

suru.34@gmail.com