CTRI/2020/02/023261尚未招募不适用
Comparative Evaluation of Anaesthetic Success after Ketorolac and Pregabalin Oral Premedication for Inferior Alveolar Nerve Block with Buccal Infiltration in Symptomatic Mandibular Molars with Irreversible Pulpitis-- A Prospective, Randomized, Controlled, Double-Blind Study
dr suruchi agrawal1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2020年2月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- compare the effect of oral premedication with ketorolac and pregabalin on anesthetic efficacy of inferior alveolar nerve block and buccal infiltration in symptomatic patients with irreversible pulpitis
研究概览
简要总结
This is a prospective, randomized, controlled, double blind study will be to achieve maximum anaesthetic success using ketorolac and pregabalin premedication with 1.7mL of articaine IANB with BI in teeth with symptomatic IP. Sample size of this trial is 150 which is divided into three groups of 50 each. All patients will be asked to rate the pain on the HP VAS to analyse the level of pain during access opening and after instrumentation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Symptomatic irreversible pulpitis 2 Patients with active pain in a mandibular first or/and second molar, 3 Patients in good health, with no previous history of allergy to any kind of local anesthesia, sulphites or other drugs that would alter pain perception.
- •4 Prolonged response to cold testing with Endo-frost (Roeko Langenace, Germany) 5 Absence of any periapical radiolucency on periapical radiographs 6 A vital coronal pulp on access opening.
排除标准
- •1 Subjects younger than 18 years and older than 60 2 History of significant medical problems 3 Taken central nervous system depressants or any analgesic medication within 8 hours 4 Pregnancy 5 Allergy to articaine, ketorolac, pregabalin 6 Unable to give informed consent.
结局指标
主要结局
compare the effect of oral premedication with ketorolac and pregabalin on anesthetic efficacy of inferior alveolar nerve block and buccal infiltration in symptomatic patients with irreversible pulpitis
时间窗: pain assessment done at 15 minutes
次要结局
未报告次要终点
研究者
研究点 (1)
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