NCT01478165已完成不适用
Comparative Study of TIVA(Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing PONV(Postoperative Nausea and Vomiting)
Incheon St.Mary's Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2011年9月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Incidence of postoperative nausea and vomiting
研究概览
简要总结
A total intravenous anesthesia (TIVA) is a useful anesthetic technique that reduces the incidence of postoperative nausea and vomiting (PONV).
Investigator hypothesized the incidence of PONV can be further reduced when palonosetron is added to TIVA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •ASA Physical Status 1 or 2
- •Elective gynaecological laparoscopic surgery of ≥ 1h duration
排除标准
- •Anti-emetics, steroids, or psychoactive medications within 24 h of study initiation
- •Vomiting or retching in the 24 h preceding surgery
- •Cancer chemotherapy within 4 weeks or emetogenic radiotherapy within 8 weeks before study entry
- •Ongoing vomiting from gastrointestinal disease
研究组 & 干预措施
Tiva group (Group T)
Placebo Comparator
干预措施: Total intravenous anesthesia (Drug)
TIVA plus palonosetron group (Group T+P)
Active Comparator
干预措施: Total intravenous anesthesia plus palonosetron (Drug)
结局指标
主要结局
Incidence of postoperative nausea and vomiting
时间窗: For 24 hours after surgery
次要结局
- Severity of nausea(For 24 hours after surgery)
研究者
Soo Kyoung Park
Clnical professor
Incheon St.Mary's Hospital
研究点 (1)
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