A clinical study of the restored kidney transplantation from living donors with small renal tumors by nephrectomy

Not Applicable

Recruiting

• Conditions: For Donor:small renal tumors For Recipient:End stage chronic renal failure

• Registration Number: JPRN-UMIN000025832
• Lead Sponsor: Tokushukai Medical Group

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-01-24
• Last Update Posted: 17 October 2023
• Study Completion: 2029-06-30

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Not provided

Exclusion Criteria

For Donor: 1. Patients who have received anti-cancer drugs (including molecular targeted drugs, cytokines, etc.) or other drugs within one month of nephrectomy. 2. Patients with a history of irradiation of the kidney to be removed. 3. Suspected renal tumours such as malignant lymphoma or sarcoma, or malignant tumours outside the kidney. 4. Comorbid infections (e.g. HIV, HBV, HCV) and serious illnesses. 5. Cases in which partial nephrectomy is deemed appropriate. 6. Cases other than those listed above, where the principal investigator performing the nephrectomy, the ethics review committee of the nephrectomy facility or the restorative renal transplantation review committee considers the case inappropriate as a subject. For Recipient: 1.The patient has an active infection, bleeding ulcer or malignancy. 2. The patient has a severe vascular or circulatory disorder (e.g. aortic aneurysm, cerebral thrombosis, myocardial infarction, thrombosis, pulmonary embolism), which may be exacerbated by transplantation. 3. Patients other than those listed above who are deemed inappropriate for inclusion by the transplant facility's principal investigator, the transplant facility's ethical review committee or the restorative renal transplant review committee.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
For Recipient: Renal viability rate from post-renal transplantation to 5 years post-operatively

Secondary Outcome Measures

Name	Time	Method
For Donor and Recipient: occurrence of cancer and patient survival from post-renal transplantation to 5 years post-operatively