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Clinical Trials/NCT07604428
NCT07604428CompletedNot Applicable

Intraocular Pressure Changes During Dry Static Apnea in Breath-Hold Divers

University Hospital Olomouc1 site in 1 country40 target enrollmentStarted: January 1, 2018Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
40
Locations
1

Study Overview

Brief Summary

This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers. Forty participants performed voluntary breath-holds while intraocular pressure, peripheral oxygen saturation (SpO2), heart rate, and blood pressure were measured at baseline, during apnea, and after apnea. The aim was to assess the magnitude and dynamics of IOP changes and their relationship to physiological parameters.

Detailed Description

Breath-hold diving is associated with marked physiological changes, including hypoxemia, hypercapnia, bradycardia, and increases in blood pressure. The effect of prolonged breath-holding on intraocular pressure (IOP) remains insufficiently understood.

This prospective observational study investigated changes in intraocular pressure during dry static apnea (STA) in adult breath-hold divers. Participants performed breath-holds in a supine position after a standardized resting period.

Intraocular pressure was measured using a rebound tonometer (Icare Pro, Icare Finland Oy, Helsinki, Finland). Blood pressure was measured using an automated sphygmomanometer (Omron M6 Comfort, Omron Healthcare, Kyoto, Japan). Peripheral oxygen saturation and heart rate were continuously monitored using a pulse oximeter (Beurer PO 80, Beurer Healthcare, Germany).

Measurements were obtained at baseline, during apnea and after resumption of breathing.

The primary objective was to quantify changes in intraocular pressure during STA. Secondary objectives included assessment of physiological responses and analysis of their relationship with IOP changes.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • age over 18 years
  • breath-hold divers at the amateur or professional level
  • signed informed consent

Exclusion Criteria

  • known intraocular hypertension or glaucoma
  • refractive error > ±5.00 D
  • history of an eye injury
  • previous surgery for cataract, strabismus, or pars plana vitrectomy
  • corneal disease
  • acute eye infection

Investigators

Sponsor
University Hospital Olomouc
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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