A comparison of carbetocin and oxytocin in prevention of uterine atony following emergency Caesarean sectio
- Conditions
- Post delivery via emergency caesarean sectionPregnancy and ChildbirthSingle delivery by caesarean section
- Registration Number
- ISRCTN18976822
- Lead Sponsor
- niversity Malaya Medical Centre (Malaysia)
- Brief Summary
2016 results in https://pubmed.ncbi.nlm.nih.gov/26773246/ (added 29/12/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 547
Women of 18 years or older with a term (more than 37 weeks period of gestation), singleton pregnancy who will be undergoing an emergency Lower Segment Caesarean Section (LSCS) under regional anaesthesia.
An emergency LSCS has been defined as an unplanned LSCS which is performed once labour has commenced or during the process of labour for any reasons indicated. Labour in this context has been defined as documented regular contractions with frequency of at least once in 10 minutes with cervical dilatation of 3cm and more.
1. Suspected or known coagulopathy
2. Hypersensitivity to the study drugs
3. History of heart disease including
3.1. Cardiac arrhythmia
3.2. Hypertension
3.3. Evidence of liver, renal or endocrine diseases (other than gestational diabetes)
4. LSCS is done under general anaesthesia for any reason
5. Diagnosed placenta praevia
6. Placental abruption
7. Fibroid in pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eed for additional uterotonic intervention within 24 hours after LSCS to maintain the adequacy of uterine tone as judged by the attending surgeon and clinician.
- Secondary Outcome Measures
Name Time Method <br> 1. Drop in haemoglobin and haematocrit level by 24 hours postoperatively<br> 2. Total estimated blood loss<br> 3. Vital signs<br> 4. Side effects<br> 5. Operating time<br> 6. Need for blood transfusion<br>