Calorie Anticipation and Food Intake

Not Applicable

Completed

• Conditions: Eating Behaviour; Obesity
• Interventions: Behavioral: low calorie yogurt; Behavioral: high calorie yogurt

• Registration Number: NCT01680315
• Lead Sponsor: Uppsala University

Brief Summary

The regulation of our food intake is on the short-term guided by appetite and satiety signals generated by the sight and consumption of food. Food intake is not only regulated by appetite and satiety signals - external cues also play an important role.

It has been observed that food intake and the pleasure derived from consumption is affected by manipulation of the external cues.

The investigators will assess the contribution of food anticipation (calorie information) and actual consumption of a test food (calorie intake) on in satiety responses (such as ghrelin responses, appetite and subsequent food intake). The investigators expect the information on the amount of calories, rather than the actual amount of calories in the food, to predict the ghrelin responses and the subsequent intake of a second meal.

Detailed Description

In a randomized cross-over design with 4 conditions, all participants will consume twice the low-caloric food (once with the low-calorie information and once with the high-calorie information) and twice the high-caloric food (again, once with the low-calorie information and once with the high-calorie information) in a randomized order.

Study Timeline

• Study Start: 2012-05
• Primary Completion: 2012-07
• Status Verified: 2012-08
• Study Completion: 2012-08
• Study First Submitted: 2012-08-28
• Study First Submitted QC: 2012-09-03
• Last Update Submitted: 2012-09-03
• Study First Posted: 2012-09-07
• Last Update Posted: 2012-09-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 12

Inclusion Criteria

• female
• healthy
• being used to eat breakfast regularly (≥ 5 times a week).

Exclusion Criteria

• hypersensitivity for the ingredients of the foods under study;
• lack of appetite; following an energy-restricted diet or change in body weight > 5 kg; or
• being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Calorie information	low calorie yogurt	Low calorie yogurt High calorie yogurt with low calorie information sheet
Calorie information	high calorie yogurt	Low calorie yogurt High calorie yogurt with low calorie information sheet
Calorie information (high)	low calorie yogurt	Low calorie yogurt High calorie yogurt High calorie information sheet
Calorie information (high)	high calorie yogurt	Low calorie yogurt High calorie yogurt High calorie information sheet

Primary Outcome Measures

Name	Time	Method
Food intake	60 min (Ad libitum test meal after 1 hr)

Secondary Outcome Measures

Name	Time	Method
Serum concentrations total ghrelin	60 min (4 samples - every 20 min)

Trial Locations

Locations (1)

Uppsala University; 🇸🇪 Uppsala, Sweden