ACTRN12615000600549
Completed
Phase 3
Effects of testosterone and exercise (TEX) on fitness, physical activity and vascular health in men aged 50-70 years with waist circumference 95 cm or more: a 2x2 factorial randomised controlled trial.
Dr Bu Yeap0 sites80 target enrollmentJune 9, 2015
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Dr Bu Yeap
- Enrollment
- 80
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Men aged 50\-70 years with waist circumference 95 cm or more. Total cholesterol 7\.0 mmol/L or less, or LDL 4\.0 mmol/L or less, eGFR 45 ml/min or more, and total testosterone 6\-14 nmol/L with normal haematocrit and PSA, and no evidence of significant liver disease. No clinical indication of pituitary, testicular or prostate disease, and office BP 150 mmHg systolic or less and 95 mmHg diastolic or less.
Exclusion Criteria
- •Cardiovascular disease shown by history of angina, hospitalisation for myocardial infarction, stroke, heart failure or peripheral artery disease, prostate cancer or other major medical comorbidity (eg. renal or lung disease or cancer, transplantation or use of high dose opiate therapy).
Outcomes
Primary Outcomes
Not specified
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