Analysis of dental biofilm's proteins and its relation with the effectiveness of the resin infiltration technique to prevent tooth breakdown in children who present molar-incisor hypomineralization (MIH)
Not Applicable
Recruiting
- Conditions
- Dental caries
- Registration Number
- RBR-5bphrt
- Lead Sponsor
- Faculdade de Ciências da Saúde - Universidade de Brasília
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Children with 8 years old; with good general health; with the first four permanent molars erupted, with at least one being affected by molar-incisive hypomineralization (MIH); who sign the terms of assent; whose parents have signed the TCLEs.
Exclusion Criteria
Children who have used any antifungal drug therapy or topical oropharyngeal antimicrobial medications for at least three months prior to collection; children outside the established age range; children with systemic, motor or psychological impairment.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Based on previous studies carried out in a population residing in the same region, it was estimated that the resin infiltration technique is able to reduce in half the loss of dental structure in MIH permanent molars that have white or yellowish-brown demarcated opacities, compared to the control group over a 24-month period<br>
- Secondary Outcome Measures
Name Time Method It is expected that there is correlation between the quality and amount of supragingival biofilm of the teeth evaluated with their protein profile and caries activity