Acupuncture for diminished ovarian reserve: a patient registry study

Not Applicable

Conditions: Diminished ovarian reserve

Registration Number: ITMCTR2200006405

Lead Sponsor: Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: Not specified

Inclusion Criteria

(1) Meet the diagnostic criteria of DOR;
(2) 18 years = age < 40 years.
(3) Voluntary participation and informed consent.

Exclusion Criteria

(1) Polycystic ovary syndrome, hyperprolactinemia, hyperandrogenemia, hypothyroidism and other endocrine diseases affect ovulation;
(2) DOR caused by iatrogenic factors (such as pelvic surgery, radiotherapy and chemotherapy, uterine artery embolization, drugs such as hormones, immunosuppressants, etc.);
(3) Have taken hormone drugs (such as contraceptives, glucocorticoids, etc.) in the past three months (except those required for in vitro fertilization-embryo transfer);
(4) Patients with severe anxiety with a Self-Rating Anxiety Scale(SAS) score > 70;
(5) Combined with serious cardiovascular, cerebrovascular, liver, kidney, malignant tumor, hematopoietic system and mental diseases.

Study & Design

Study Type: Observational study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical prenancy rate;

Secondary Outcome Measures

Name	Time	Method
Embryo implantation rate;Available embryo rate;Uterine artery blood flow resistance index (RI);Endometrial volume;Menstrual volume;Live birth rate;Basal serum level of FSH;Basal serum level of FSH/LH;Endometrial thickness;AMH;Endometrial morphology;Uterine artery blood flow pulsation index (PI);SAS score;Endometrial vascularization flow index (VFI);Early pregnancy loss rate;Basal serum level of LH;Endometrial vascularization index (VI);AFC;Continuous pregnancy rate;Biochemical pregnancy rate;Basal serum level of E2;High-quality embryo rate;Menstrual duration;Endometrial flow index (FI);Number of eggs harvested;Menstrual cycle;