The efficacy of rTMS on non-suicidal self-injurious behavior and its brain function changes in adolescent patients with depressive disorders
Phase 1
- Conditions
- depression
- Registration Number
- ChiCTR2400089012
- Lead Sponsor
- The First Affiliated Hospital of the People's Liberation Army Air Force Military Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Be 10-19 years of age;<br>2) Meets DSM-5 criteria for the diagnosis of depressive disorder;<br>3) Hamilton Depression Scale (HAMD-17) score >17;<br>4) Meeting DSM-5 criteria for diagnosis of non-suicidal self-injury;<br>5) not have a score of 0 on the Adolescent Non-Suicidal Self-Injury Behavior Rating Questionnaire (ANSAQ);<br>6) no history of any form of antidepressant treatment (including medication, physical and psychotherapy) within 4 weeks prior to enrollment;<br>7) Habitual use of the right hand;<br>8) Be fully aware of the safety of rTMS, and cooperate actively with the treatment voluntarily;Able to comply with the schedule, cooperate with the completion of the study, and sign the informed consent form with the guardian.
Exclusion Criteria
- Have organic brain disease;<br>2) having a serious somatic disease; and<br>3) Having other serious mental illnesses;<br>4) Having previous epileptic seizures;<br>5) Have instruments installed in the body that are not suitable for rTMS treatment, such as pacemakers, artificial valves, cochlear implants and other metal implants; Have strong suicidal ideation.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adolescent Non-suicidal Self-injury Assessment Questionnaire;
- Secondary Outcome Measures
Name Time Method Hamilton depression scale;Hamilton Anxiety Scale;Simplified Coping Style Questionnaire;functional near-infrared spectroscopy;