A Study to find markers in blood and cerebrospinal fluid to help diagnose tuberculosis of the brai
Not Applicable
- Conditions
- Health Condition 1: A179- Tuberculosis of nervous system, unspecified
- Registration Number
- CTRI/2020/04/024423
- Lead Sponsor
- niversity Hospital Frankfurt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Clinically suspected Central Nervous System Tuberculosis
Exclusion Criteria
•Informed consent not given
•Lumbar puncture not possible/not performed before start of treatment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢Diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of biomarkers for differentiating CNS Tb and clinically relevant differential diagnosis (sarcoidosis, lymphoma, other infectious cause) <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: Baseline ( Date of Patient Enrollment ) and follow-up at 6 months
- Secondary Outcome Measures
Name Time Method â?¢Diagnostic accuracy (sensitivity, specificity, positive predictive value, negative predictive value) of biomarkers at 6 month follow up for treatment success and clinical outcomeTimepoint: Baseline ( Date of Patient Enrollment ) and follow-up at 6 months