Comparison of opioid versus opioid free anaesthesia with ketamine and lidocaine on post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy.
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056869
- Lead Sponsor
- school of medical sciences and research,sharda university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.ASA I and II
2.Age 18-60yrs
3.Both genders
4.Surgeries = 2 hours
Exclusion Criteria
1.BMI > 30 kg m¬-2
2.Pregnant females
3.Patients having history of motion sickness and migraine.
4.Patients having history of drug allergy to ketamine and lidocaine.
5.Patients having history of respiratory, cardiovascular, renal, hepatic and endocrine disease and psychosis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of fentanyl (opioid) versus ketamine & lidocaine (opioid free) anaesthesia on post-operative nausea and vomiting in laparoscopic cholecystectomy.Timepoint: Post operative 24 hours
- Secondary Outcome Measures
Name Time Method To compare the effect of fentanyl (opioid) versus ketamine & lidocaine (opioid free) anaesthesia in laparoscopic cholecystectomy with regard to: <br/ ><br>1.VAS Score for post-operative pain. <br/ ><br>2.Duration of analgesia in post-operative period. <br/ ><br>3.Sedation score postoperatively. <br/ ><br>4.The duration of discharge from PACU. <br/ ><br> <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: 24 hours