Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension

Institute of liver and Biliary Sciences0 个研究点目标入组 308 人开始时间: 待定最近更新: 2021年11月24日

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•1) Cirrhotic patients of any aetiology with Infection - suspected or documented and Mean arterial pressure less than 65 mm of Hg or systolic blood pressure

•1)Cirrhosis patients in septic shock who are already on vasopressors and/or inotropes
•2)Cirrhosis patients in septic shock with structural heart disease
•3)Cirrhosis patients in septic shock with chronic renal failure/dialysis dependent/volume overloaded state
•4)Cirrhosis patients in shock, caused by other reasons, other than septic shock
•5)Cirrhosis patients in septic shock in whom contraindication to internal jugular or subclavian line insertion is present
•6)Age less than 18 years
•7)Previous episode of septic shock during the same hospital stay
•8)Pregnant or lactating women
•9)Patients in need for emergent surgical interventions
•10)Cirrhosis patients in septic shock with chronic obstructive lung disease and right heart failure
•11)Cirrhosis patients in septic shock with associated upper gastrointestinal bleed or coagulopathy related bleed with a haemoglobin of less than 8g/dL or requiring urgent transfusions of blood and blood products
•12)A previous adverse reaction to human albumin solution

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