Role of sTREM-1, IL-1B,and MMP-8 as salivary biomarkers in patients with Periodontitis and Type 2 Diabetes Mellitus

Saranya B0 个研究点目标入组 68 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Group I: Systemically healthy subjects with clinically healthy gingiva
•1) No bleeding on probing, normal probing sulcus depth and bone levels (According to 2017 classification)
•Group II: Systemically healthy subjects with Stage III or IV periodontitis
•1) Generalized sites with PPD and CAL more than or equal to 6mm, 5mm respectively. Radiographic bone loss till middle or apical third of root (According to 2017 classification)
•Group III: Subjects with Type 2 Diabetes Mellitus with clinically healthy gingiva
•1) HbA1c levels 6.5-7.9%
•2) Periodontal status according to 2017 classification
•Group IV: Subjects with Type 2 Diabetes Mellitus with Stage III or IV periodontitis
•1) HbA1c levels 6.5-7.9%
•2) Periodontal status according to 2017 classification

•1) Pregnant and lactating women
•2) Patients with immunodeficiency disorders
•3) Patients with other systemic inflammatory conditions like sepsis, pneumonia, intra-abdominal infections, inflammatory bowel disorders, chronic kidney disease, atherosclerosis, COPD, asthma, hepatitis.
•4) History of periodontal treatment in past 6 months.
•5) History of antibiotic therapy in past 3 months.
•6) Subjects who are not willing to participate in study.

发起方

Saranya B