efficacy of Fluorometholone versus Loteprednol eye drops after photorefractive keratectomy

Phase 3

• Conditions: Condition 1: Myopia correction by photorefractive keratectomy. Condition 2: Astigmatism correction by photorefractive keratectomy.; Myopia, unspecified eye; Unspecified astigmatism; H52.10; H52.20

• Registration Number: IRCT20131229015975N6
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Stable refraction error for at least 12 months
Myopia between -8.0 to -1.0 diopters
Astigmatism less than 4.0 diopters
Normal eye examination

Exclusion Criteria

Unwillingness to participate or continue
administration of another topical medication
need to increase the topical steroid dosage
treatment-related complications

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in best corrected distance visual acuity (BCDVA). Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Eye examination, slit-lamp biomicroscopy and fundus examination assessment.;Corneal optical density. Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Corneal densitometry was performed with a rotating camera cornea tomography system (Pentacam®).

Secondary Outcome Measures

Name	Time	Method
Intraocular pressure. Timepoint: Before intervention and on days one, three, and five and then at months one and three postoperatively. Method of measurement: Goldman applanation tonometry (GAT).;Side effects. Timepoint: On days one, three, and five and then at months one and three postoperatively. Method of measurement: Clinical assessment.