To Explore the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders in Patients Undergoing Cardiovascular Surgery Under General Anaesthesia: a Single-centre Prospective Observational Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiovascular Surgery
- Sponsor
- Beijing Chao Yang Hospital
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery
- Status
- Recruiting
- Last Updated
- 11 months ago
Overview
Brief Summary
To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia
Detailed Description
Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA). Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Written informed consent
- •undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia
- •ASA grade: II-IV
- •older than 60 years
- •Able to complete cognitive function tests
- •Exclusion criteria:
- •history of severe neurological diseases and psychiatric diseases
- •history of drug abuse
- •severe hearing or vision impairment
- •preoperative delirium
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
The predictive value of preoperative Electroencephalography features in patients with postoperative cognitive dysfunction following cardiovascular surgery
Time Frame: 2025.08
Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery. Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using The Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).
Secondary Outcomes
- The predictive value of preoperative Electroencephalography features in patients with postoperative delirium following cardiovascular surgery(2025.08)
- Electroencephalography features in patients with postoperative delirium(2025.08)