Clinical and laboratory study on the effects of green tea on the treatment of patients with Smear positive TB

Not Applicable

• Conditions: Respiratory Tuberculosis.; Tuberculosis of lung, confirmed by sputum microscopy with or without culture

• Registration Number: IRCT201212232602N11
• Lead Sponsor: Research Council of Golestan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Definitive diagnosis of TB according to Ministry of Health criteria; Location in Golestan Province ; treatment of patients under DOTS strategy; Age 15 years and over; Willingness to cooperate in study
Exclusion criteria : Allergic symptoms or side effects of green tea consumption; Severe changes in liver function tests due to anti-TB drugs; Side-effects of anti-TB drugs

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sputum smear conversion. Timepoint: from day 20 to 60 every 10 days. Method of measurement: microscopic smear of sputum.

Secondary Outcome Measures

Name	Time	Method
Hemoglobin. Timepoint: begining of treatment and end of second month. Method of measurement: laboratory measurement.;Transferrin receptor gene expression. Timepoint: begining of treatment and end of second month. Method of measurement: real time PCR.;Hepcidin gene expression. Timepoint: begining of treatment and end of second month. Method of measurement: real time PCR.;TIBC. Timepoint: begining of treatment and end of second month. Method of measurement: laboratory measurement.;Transferrin. Timepoint: begining of treatment and end of second month. Method of measurement: laboratory measurement.;Ferritin. Timepoint: begining of treatment and end of second month. Method of measurement: laboratory measurement.