Comparison of Different Anthropometric Parameters in Relation to Cardiometabolic Risk Factors in a Cohort of Subjects With Overweight and Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,214
- 试验地点
- 1
- 主要终点
- waist circumference
研究概览
简要总结
The study was aimed at comparing four different anthropometric parameters to cardiometabolic risk factors in overweight and obese subjects (Body Mass Index (BMI)≥25)
详细描述
the present study was focused to compare the level of statistical association among four different anthropometric parameters, body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR) and neck circumference (NC) and the cardiovascular (CV) risk factors most commonly evaluated in the clinical practice such as systolic and diastolic blood pressure, and fasting glucose, lipid (triglycerides, total, High-density lipoprotein (HDL) and Low-density lipoprotein (LDL) cholesterol), insulin, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), uric acid, 25-hydroxyvitamin D (25(OH)D), c-reactive protein (CRP), white blood cells and platelet number in a population of 1214 apparently healthy subjects with overweight and obesity subjects
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Overweight or obesity (BMI> 25 Kg/m2)
排除标准
- •Any kind of drug
- •Hypertension
- •Endocrine diseases (diabetes mellitus, hypo or hyperthyroidism, hypopituitarism, etc.),
- •Chronic inflammatory diseases
- •Renal failure
- •Liver failure
- •Angina pectoris
- •Myocardial infarction and heart failure
- •Genetic heart diseases
- •Thrombocytopenias
结局指标
主要结局
waist circumference
时间窗: baseline
waist circumference (WC) (expressed in cm)
Body mass index
时间窗: baseline
Body mass index (BMI) (expressed in kg/m\^2)
neck circumference
时间窗: baseline
neck circumference (NC) (expressed in cm)
waist to height ratio
时间窗: baseline
waist to height ratio (WHtR)
次要结局
- Triglyceride(baseline)
- Homeostasis model assessment: insulin resistance(baseline)
- Platelets(baseline)
- Blood pressure(baseline)
- Intima-media thickness(baseline)
- Total Cholesterol(baseline)
- fasting blood glucose(baseline)
- Insulin(baseline)
- Vitamin D(baseline)
- C-reactive Protein(baseline)
- HDL Cholesterol(baseline)
- LDL Cholesterol(baseline)
- white blood cells(baseline)
研究者
Gianluigi Giannelli
Clinical Professor
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis