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临床试验/NCT05810506
NCT05810506已完成不适用

Evaluation of Anthropometric Measurements and Biochemical Parameters in Non-Alcoholic Fatty Liver Patients and Healthy Individuals

Bandırma Onyedi Eylül University1 个研究点 分布在 1 个国家目标入组 82 人开始时间: 2021年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
82
试验地点
1
主要终点
Body fat percentage

研究概览

简要总结

The aim of this study; Which anthropometric measurement and ratio (BMI, waist circumference, hip circumference, waist-to-hip ratio, neck circumference, waist-height ratio, body shape index, body roundness index, visceral adiposity index) is a better indicator in healthy individuals with NAFLD and their biochemical parameters is to evaluate.

详细描述

NAFLD patients included in the study should sign a voluntary consent form, do not consume alcohol, be between 30-64 years old, have been diagnosed with NAFLD by applying to the gastroenterology outpatient clinic, have no other diseases, and should not use medication. Healthy individuals; they were required to sign the voluntary consent form, not consume alcohol, be between 30-64 years old, and not have any acute or chronic diseases. Individuals outside these criteria were not included in the study. The reason for the 30-64 age limit for individuals with NAFLD in the study is that NAFLD is more common in this age group. The same criteria were also taken into account in healthy individuals to avoid differences between groups. Individuals who met the inclusion criteria of the study and accepted to participate in the study voluntarily were selected by random sampling method and the sample of the study was formed. For the study, research permission was obtained from Gülhane Training and Research Hospital and ethical approval of the study from Ankara University Ethics Committee (56786525-050.04.04/236883). Written and verbal consent was obtained from the patients before starting the study. The research was conducted in accordance with both the Declarations of Helsinki and Istanbul. Biochemical Parameters Fasting blood glucose, total cholesterol, triglyceride, HDL, VLDL, LDL, ALP, AST, ALT and GGT values of the individuals participating in the study were obtained from the files with the permission of the patients.

Anthropometric Measurements The data were collected using a questionnaire form and face-to-face interview method. In the study, individuals' body weight (kg), height (cm), waist circumference (cm), hip circumference (cm), neck circumference (cm) measurements were taken in accordance with the method, and these measurement values were used to measure BMI, waist-height ratio, waist-hip ratio, body composition (fat mass, muscle mass, etc.), body shape index, body roundness index, visceral adiposity index measurements were calculated. Body mass index was calculated by dividing the body weight by the square of the height. Other anthropometric measurements and ratios were calculated using appropriate formulas.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 64 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Body fat percentage

时间窗: Six month

The body fat mass of individuals will be measured with the TANITA BC-418 MA BIA analyzer.

Waist circumference

时间窗: Six month

The patient's side will be passed to the side of the patient and the circumference passing through the middle point will be measured between the lowest point of the rib bone and the iliac crest.

Height

时间窗: Six month

The height of the patients will be measured with a stadiometer while the feet are together and the head is in the Frankford plane.

Body roundness index

时间窗: Six month

The body roundness index of the patients will be calculated using the formula \[364.2-365.5x√1-\[(waist circumference/(2π))2/(0.5 x height)2\].

Neck circumference

时间窗: Six month

Measure with a non-stretchable tape measure horizontally at the upper edge of the laryngeal prominence with the head upright and eyes facing forward.

Waist to hip ratio

时间窗: Six month

It is the ratio of waist circumference to hip circumference.

Body mass index

时间窗: Six month

It will be calculated by dividing the body weight by the square of the height

Waist-to-length ratio

时间窗: Six month

It is the ratio of waist circumference to height.

Body weight

时间窗: Six month

Body weight measurements of the patients will be made by removing thick clothes and shoes, and by means of TANITA BC-418 MA brand Bioelectrical Impedance Analysis (BIA).

Hip circumference

时间窗: Six month

The largest circumference between the waist and knees will be measured by going to the side of the patient.

Body shape index

时间窗: Six month

Body shape index of patients; with height, waist circumference and BMI values; It will be calculated using the formula \[Waist circumference/ (BKİ )2/3\* Height 1/2\].

Visceral adiposity index

时间窗: Six month

Patients' visceral adiposity index for men: \[Waist circumference/ 39.68 + (1.88 × \[BMI\])\] × \[(TG)/1.03\] × (1.31/HDL); for women: will be calculated using the formulas \[Waist circumference /36.58 + (1.89 × BMI)\] × (TG/0.81) × (1.52/HDL).

次要结局

未报告次要终点

研究者

发起方
Bandırma Onyedi Eylül University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Tuba ONAY

Research Assistant Doctor /Principal İnvestigator

Bandırma Onyedi Eylül University

研究点 (1)

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