Evaluation of Anthropometric Measurements and Biochemical Parameters in Non-Alcoholic Fatty Liver Patients and Healthy Individuals
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Non-Alcoholic Fatty Liver Disease
- Sponsor
- Bandırma Onyedi Eylül University
- Enrollment
- 82
- Locations
- 1
- Primary Endpoint
- Body fat percentage
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The aim of this study; Which anthropometric measurement and ratio (BMI, waist circumference, hip circumference, waist-to-hip ratio, neck circumference, waist-height ratio, body shape index, body roundness index, visceral adiposity index) is a better indicator in healthy individuals with NAFLD and their biochemical parameters is to evaluate.
Detailed Description
NAFLD patients included in the study should sign a voluntary consent form, do not consume alcohol, be between 30-64 years old, have been diagnosed with NAFLD by applying to the gastroenterology outpatient clinic, have no other diseases, and should not use medication. Healthy individuals; they were required to sign the voluntary consent form, not consume alcohol, be between 30-64 years old, and not have any acute or chronic diseases. Individuals outside these criteria were not included in the study. The reason for the 30-64 age limit for individuals with NAFLD in the study is that NAFLD is more common in this age group. The same criteria were also taken into account in healthy individuals to avoid differences between groups. Individuals who met the inclusion criteria of the study and accepted to participate in the study voluntarily were selected by random sampling method and the sample of the study was formed. For the study, research permission was obtained from Gülhane Training and Research Hospital and ethical approval of the study from Ankara University Ethics Committee (56786525-050.04.04/236883). Written and verbal consent was obtained from the patients before starting the study. The research was conducted in accordance with both the Declarations of Helsinki and Istanbul. Biochemical Parameters Fasting blood glucose, total cholesterol, triglyceride, HDL, VLDL, LDL, ALP, AST, ALT and GGT values of the individuals participating in the study were obtained from the files with the permission of the patients. Anthropometric Measurements The data were collected using a questionnaire form and face-to-face interview method. In the study, individuals' body weight (kg), height (cm), waist circumference (cm), hip circumference (cm), neck circumference (cm) measurements were taken in accordance with the method, and these measurement values were used to measure BMI, waist-height ratio, waist-hip ratio, body composition (fat mass, muscle mass, etc.), body shape index, body roundness index, visceral adiposity index measurements were calculated. Body mass index was calculated by dividing the body weight by the square of the height. Other anthropometric measurements and ratios were calculated using appropriate formulas.
Investigators
Tuba ONAY
Research Assistant Doctor /Principal İnvestigator
Bandırma Onyedi Eylül University
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Body fat percentage
Time Frame: Six month
The body fat mass of individuals will be measured with the TANITA BC-418 MA BIA analyzer.
Waist circumference
Time Frame: Six month
The patient's side will be passed to the side of the patient and the circumference passing through the middle point will be measured between the lowest point of the rib bone and the iliac crest.
Height
Time Frame: Six month
The height of the patients will be measured with a stadiometer while the feet are together and the head is in the Frankford plane.
Body roundness index
Time Frame: Six month
The body roundness index of the patients will be calculated using the formula \[364.2-365.5x√1-\[(waist circumference/(2π))2/(0.5 x height)2\].
Neck circumference
Time Frame: Six month
Measure with a non-stretchable tape measure horizontally at the upper edge of the laryngeal prominence with the head upright and eyes facing forward.
Waist to hip ratio
Time Frame: Six month
It is the ratio of waist circumference to hip circumference.
Body mass index
Time Frame: Six month
It will be calculated by dividing the body weight by the square of the height
Waist-to-length ratio
Time Frame: Six month
It is the ratio of waist circumference to height.
Body weight
Time Frame: Six month
Body weight measurements of the patients will be made by removing thick clothes and shoes, and by means of TANITA BC-418 MA brand Bioelectrical Impedance Analysis (BIA).
Hip circumference
Time Frame: Six month
The largest circumference between the waist and knees will be measured by going to the side of the patient.
Body shape index
Time Frame: Six month
Body shape index of patients; with height, waist circumference and BMI values; It will be calculated using the formula \[Waist circumference/ (BKİ )2/3\* Height 1/2\].
Visceral adiposity index
Time Frame: Six month
Patients' visceral adiposity index for men: \[Waist circumference/ 39.68 + (1.88 × \[BMI\])\] × \[(TG)/1.03\] × (1.31/HDL); for women: will be calculated using the formulas \[Waist circumference /36.58 + (1.89 × BMI)\] × (TG/0.81) × (1.52/HDL).