Efficacy of calcitriol therapy in CKD, based on Vitamin D receptor gene polymorphisms
Not Applicable
- Conditions
- Health Condition 1: N183- Chronic kidney disease, stage 3 (moderate)Health Condition 2: N184- Chronic kidney disease, stage 4 (severe)Health Condition 3: N185- Chronic kidney disease, stage 5
- Registration Number
- CTRI/2020/07/026536
- Lead Sponsor
- Indian Council of Medical Research ICMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
250 adult patients (18 to 65yrs) with CKD (stages 3, 4 and 5; not on dialysis) would be enrolled for the study after informed consent for this study.
CKD is defined as deranged renal function for more than 3 months with/without evidence of proteinuria. Staging of CKD would be done as per KDOQI guidelines using eGFR by Modification of diet in renal disease (MDRD) formula.
Exclusion Criteria
Patients already on vitD replacement therapy would be excluded. Any other co-morbidities requiring vitD supplementation would be excluded from the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method