Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.

Not Applicable

Completed

• Conditions: Hypertrophy; Osteoarthritis, Knee

• Registration Number: NCT05058794
• Lead Sponsor: Riphah International University

Brief Summary

The main objective of the study is to compare the effects of Blood flow Restriction training vs. traditional exercises on knee pain , knee functional disability and on quadriceps strength in patient with knee osteoarthritis.

Detailed Description

Osteoarthritis is a degenerative disease affecting the most commonly weight bearing joint.The common form of arthritis is osteoarthritis (OA) causing structural changes in the joint. Age is a common factor affecting the strength and muscle mass.Worldwide there is a drastic increase of osteoarthritis in the older population. In the past 20 years the prevalence of knee pain increased and reached up to 50% in the older population. The most common OA affecting lower extremity is in the knee Joint.Majority of the people affected by knee OA are the older population. Knee Joints being the most weight bearing joint affected in OA causing pain , limiting function and mobility.Mobility and function may be affected in osteoarthritic population usually experience pain and stiffness.

The main objective of this study is to compare the Effects of blood Flow restriction training vs conventional treatment exercises on knee pain, functional disability and quadriceps strengthening.

The main purpose of this study is to improve the muscular strength of lower limbs which are being affected in a disease osteoarthritis in the adult population.

Study Timeline

• Study First Submitted: 2021-09-17
• Study First Submitted QC: 2021-09-17
• Study First Posted: 2021-09-28
• Study Start: 2021-10-10
• Primary Completion: 2022-02-11
• Study Completion: 2022-02-11
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-08
• Last Update Posted: 2022-03-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Pain : Subjects having unilateral or bilateral pain
• Pain type : subjects having chronic pain
• Includes diagnosed cases of knee osteoarthritis
• grades 2-3 according to the Kellgren and Lawrence method of grading
• Includes knee osteoarthritis patients with lateral tracking of patella which will assessed through Q angle test

Exclusion Criteria

• Any other orthopaedic or neurological condition of hip and knee
• Sign and symptoms of lower motor neuron disease
• Current use of medication
• Radiculopathy
• Fracture
• Malignancy
• Thromboembolism
• Decreased range of motion

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Muscle strength	6 weeks	Measurement of Quadriceps strength with portable weight machine.
Thigh Girth	6 weeks	Participants will be supine lying and knee in extension, standing or knee at 90 degree. Proximal to the patellar pole superiorly one measurement with a non-elastic tape at the inguinal fold, then mark the mid-point at the mid-thigh level measuring in centimeters/inches.
Numeric Pain Rating Scale ( NPRS)	6 weeks	Patient will be asked if there is any pain in knee from the scale of 0 to 10.
Q angle Measurement	6 weeks	Subject will be in supine position with knee extension and quadriceps are relaxed, examiner will measure the q angle with flexible inch tape and goniometer. The Q- angle is measured by extending a line through the center of the patella to the anterior superior iliac spine and another line from the tibial tubercle through the center of the patella.

Trial Locations

Locations (2)

Gulberg Medical Complex; 🇵🇰 Islamabad, Federal, Pakistan

Medcity International Hospital; 🇵🇰 Islamabad, Federal, Pakistan