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The effect of azithromycin in treatment of COVID19

Phase 3
Conditions
SARS-COV2 ASSOCIATED INFECTION.
COVID-19, virus identified
U07.1
Registration Number
IRCT20200415047092N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
110
Inclusion Criteria

Obtaining informed consent from patient or patient’s legal proxy for inclusion in this study.-
Patients must be over 18 years of age-
A documented positive PCR test for SARS-CoV-2 or one of the following criteria:1.Compelling clinical symptoms associated with a covid-19 infection; including: fever, dry cough and dyspnea2.A typically involvement of lungs observed in HRCT or Spiral CT scanning that can be strongly attributed to a covid-19 pneumonia3.
Patients that have developed known complications of a covid-19 infection such as acute respiratory distress syndrome (ARDS) or myocarditis.

Exclusion Criteria

pregnancy or nursing
Patients whose covid-10 infection has not been proven and have symptoms that can be attributed to either the common cold or influenza and/or have had a positive PCR test for influenza.
known allergy to chloroquine or hydroxylchloroquine
retinopathy
G6PD deficiency
prolonged QT interval
severe heart failure
Pacemaker implantation
cardiac arrhythmia

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Peripheral capillary oxygen saturation. Timepoint: At the beginning of the visit and daily during admission. Method of measurement: pulse oximeter.;Admission duration. Timepoint: From the beginning of the hospital visit to the discharge. Method of measurement: Questionnaire.;Fever. Timepoint: At the beginning of the visit and daily during admission. Method of measurement: Mercury thermometer.;Need to ICU admission. Timepoint: During admission. Method of measurement: Questionnaire.
Secondary Outcome Measures
NameTimeMethod
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