Benefits of systemically administered adjunctive azithromycin in periodontitis patients non-responsive to initial non-surgical periodontal therapy.

Phase 3

• Conditions: Periodontitis patients' non-responsive to initial periodontal therapy; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12619000597190
• Lead Sponsor: The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-17
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

a)Diagnosis of periodontitis patients non-responsive to initial periodontal therapy will be determined by the presence of at least 4 sites with probing depth equal to or greater than 6 mm on at least two non-adjacent teeth with bleeding on probing at the recall visit after initial periodontal debridement.
b)patients in the age range of 30 to 75 years
c)Presence of at least 16 natural teeth.

Exclusion Criteria

a)use of antimicrobials within 3 months preceding the start of the study;
b)history of sensitivity to azithromycin or macrolides
c) history of cardiac arrhythmias or history of myocardial infarction
c)current smokers( equal to or greater than 10 cigarettes/day)
d) Pregnant women
e) patients with uncontrolled type II diabetes mellitus

Study & Design

• Study Type: Interventional
• Study Design: Not specified