comparing dexmedetomidine with lignocaine and plain lignocaine nebulization before intubation to control intubation response and hemodynamic changes.
Not Applicable
- Conditions
- Health Condition 1: -
- Registration Number
- CTRI/2024/01/061090
- Lead Sponsor
- Arpita Mohanty
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients posted for elective surgeries under general endotracheal anaesthesia
American Society of Anesthesiologists (ASA) physical status I and II
Age 18-60 years
Either sex
Exclusion Criteria
.ASA-III and IV
.Emergency cases
Predicted Difficulty Airway
Obese Patients (BMI >30)
Subjects On Antihypertensive Medication
Pregnancy
Known Allergy To Dexmeditomidine And Or Lignocaine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -To compare the efficacy of nebulised dexmeditomidine at a dose of 1mcg/kg and lignocaine 4mg/kg with the efficacy of nebulised lignocaine at a dose of 4mg/kg in attenuating the hemodynamic responses to laryngoscopy and intubation. <br/ ><br> <br/ ><br>Timepoint: 1 min,3 mins, 5 mins, 10 mins
- Secondary Outcome Measures
Name Time Method -Compare the dose sparing effect of two different nebulisation regimens on the amount of propofol consume during induction of general anesthesia. <br/ ><br>-To determine the incidence of sore throat. <br/ ><br>-To determine the incidence of perioperative nausea vomiting and cough.Timepoint: 1min, 3mins , 5mins, 10mins