IRCT20151227025726N27招募中3 期
Evaluation of Efficacy and Safety of Inhaled Tocilizumab in Comparison with Intravenous Tocilizumab in Hospitalized Patients with COVID-19
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 100 years（—）
- 性别
- All
入选标准
- •Patients between 18 and 100 years old.
- •Laboratory confirmed COVID-19 (Corona Virus Disease-19) with RT-PCR (Real-Time Polymerase Chain Reaction) or CT scan.
- •Have signed the consent form.
- •O2 saturation < 90% (at room air) or lung involvement >50% or respiratory rate >30
- •CRP > 75 mg/l
- •IL-6 > 15 pg/ml
排除标准
- •Allergy to Tocilizumab or one of the components of drug formulations.
- •ANC < 500 cells/mm
- •Pelatelet < 50000 cells/mm
- •Hepatic transaminases > 5 times normal range or mild increase in liver transaminases associated with signs and symptoms of liver disorder
- •History of malignancy
- •Diverticulitis
- •Positive procalcitonin and active infection (including latent or active tuberculosis infection)
- •Taking other rheumatoid drugs at the same time
研究者
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