Efficacy of fractional CO2 vaginal laser treatment of overactive bladder in Postmenopausal women : a double- blinded randomized controlled study
- Conditions
- postmenopausal women with overactive bladder symptompostmenopausal women , overactive bladder , fractional CO2 vaginal laser
- Registration Number
- TCTR20211022005
- Lead Sponsor
- Routine to research unit Siriraj Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- Female
- Target Recruitment
- 50
postmenopausal women with overactive bladder symptom which in woman complained at least 3 months, frequency of micturition on average at least 8 times per 24 hours and at least three episodes of urgency (at least grade 2 by Patient Perception of Intensity of Urgency Scale )
Receive hormone therapy within 6 months
Use a moisturizing agent or vaginal lubricant within 30 days.
Received drugs to treat overactive bladder (Antimuscarinics or beta 3 adrenoceptor agonists) within 3 months.
Botox injections treatment around the bladder over a period of 6 months.
Patient having pelvic organ prolapse at level 3 or higher
Patients who have contraindications to the use of vaginal carbon dioxide laser therapy.
Patients who have brain problems and are able to make decisions for oneself.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method overactive bladder symptoms at 2 weeks after end of the intervention ICIQ OAB Thai version
- Secondary Outcome Measures
Name Time Method quality of life at 2 weeks after end of the intervention ICIQ OAB Thai version ,side effects of fractional CO2 vaginal laser at 2 weeks after end of the intervention Patient reported outcome using a questionnaire interview