on-invasive assessment of local glucose levels and the uptake and metabolism of glucose in tumour in the human brain using Magnetic Resonance at 3T.

• Conditions: brain tumour; malignant neoplasm in the brain; 10029211

• Registration Number: NL-OMON29778
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 8

Inclusion Criteria

patients with a recurrent brain tumor.
patients who are willing to lay down in the scanner for 3 hours

Exclusion Criteria

MRI contra indication; pacemaker, cerebral clips, metal splinters, neuro stimulator, severe claustrofobia, pregnancy
Patienten die zich reeds presenteerden met epilepsie en hiervoor behandeld worden met anti-epileptica

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>During euglycemic condition (blood glucose level of ~5.3 mM) the primary<br /><br>glucose levels and the uptake and metabolic rate of 13C-labeled glucose in the<br /><br>brain are determined. The pilot study is finished when all measurements can<br /><br>successfully be performed. In this case the report of the pilot study will be<br /><br>used to design a larger study to develop the 13C-MRS method further and to<br /><br>verify the results.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>na</p><br>