Responding or not responding to training; Prediction of balance Rehabilitation Outcome from structural and functional brain networks in Cerebral Palsy

Recruiting

• Conditions: brain damage; Cerebral Palsy; 10010335

• Registration Number: NL-OMON47215
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

* diagnosis of bilateral predominantly spastic CP, with the lower limbs more involved than the upper limbs;*
* age range: 7-15 years;
* Gross Motor Function Classification System level 2;*
* able to stand independently for 2 minutes;
* Child and Parent/guardian consent;
* Sufficient cooperation & cognitive skills: able to follow simple instructions & complete the measurements.
* MRI can be performed without general anesthesia.;* criteria for children with CP specifically, not for the typically developing control children.

Exclusion Criteria

* any orthopaedic surgery or other surgical interventions in the past twelve months that might influence mobility;
* Botulinum Toxin A injections in the past six months;
* Selective dorsal rhizotomy (SDR) in the past year;
* Vestibular deficits, benign vertigo or epilepsy;
* Claustrophobia;
* A pacemaker or other non-removable magnetic metal-containing devices or objects;
* Not able to lie still for the duration of the scan;
* Not willing to hear about *incidental findings*, potential unforeseen, clinically relevant abnormalities found in the MRI images

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome of balance control that will be investigated is the<br /><br>Pediatric Balance Scale.</p><br>