Is it possible to predict the effect of balance training based on networks in the brain in children with cerebral palsy?
Recruiting
- Conditions
- Impaired balance control in children with spastic cerebral palsy
- Registration Number
- NL-OMON29671
- Lead Sponsor
- Project leader; Prof. Dr. J.G. BecherPrincipal investigator: Dr. Pieter MeynsSponsor: VU University Medical Center AmsterdamDept. of Rehabilitation Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 51
Inclusion Criteria
•diagnosis of bilateral spastic CP, lower limbs more involved than the upper limbs;*
•8-14 years;
Exclusion Criteria
•orthopaedic surgery or other surgery in the past twelve months that might influence mobility;
•Botulinum Toxin A injections in the past six months;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Pediatric Balance Scale (PBS) will be evaluated as the main outcome of balance control.
- Secondary Outcome Measures
Name Time Method Additional balance control measures, such as:<br /><br>1. ‘balance’ and ‘running speed and agility’ subtest of the Bruininks-Oseretsky Test of Motor Proficiency<br /><br>2. Trunk Control Measurement Scale<br /><br>3. Sensory Organization Test<br /><br>4. Spatio-temporal and kinematic gait parameters during unperturbed and perturbed walking<br /><br>5. Maximum Lyapunov Exponents<br /><br>6. Gait sensitivity Norm<br /><br>7. Foot Placement Estimator<br><br>Magnetic Resonance Imaging (MRI) measures of the brain, such as:<br>1. structural brain Magnetic Resonance Imaging scans (T1 & FLAIR)<br>2. Diffusion tensor imaging scans<br>3. resting-state functional MRI scans