Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community

Not Applicable

Completed

• Conditions: Aging; Cognitive Change
• Interventions: Behavioral: Active Control App; Behavioral: Adaptive Cognitive Control Trainer (ACCT)

• Registration Number: NCT04905849
• Lead Sponsor: University of California, San Francisco

Brief Summary

The goal of this study is to test the feasibility of launching a personalized digital health assessment and remediation program for the older adults in senior living communities based upon an initial characterization of these abilities. Evidence of feasibility here using these unique methodological approaches would provide empirical evidence supporting the basis for a larger-scale implementation of such digital health technologies into less controlled senior settings.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2021-05-01
• Study First Submitted: 2021-05-24
• Study First Submitted QC: 2021-05-24
• Study First Posted: 2021-05-28
• Primary Completion: 2022-10-01
• Study Completion: 2022-12-01
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-13
• Last Update Posted: 2023-09-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• Must be living at a Senior Living Community
• have own iPad and/or smartphone,
• native-English speaker.

Participation across a spectrum of cognitive abilities is desired for this study, specifically for older adults in a community setting.

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Exclusion Criteria

• Do not have any physical or cognitive limitations that would clearly prevent them from utilizing these applications as intended

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Active Control Group	Active Control App	An active control application will be used for this arm. The total training experience here will also be for 6 weeks (3 days/week), with each training session lasting \~30 minutes (not including self-paced breaks). Here an app that is matched in terms of expectancy of benefits compared to our training groups will be determined by questioning 100 naïve individuals to predict their expected improvement on each cognitive domain across a multitude of possible applications.
Adaptive Cognitive Control Trainer (ACCT)	Adaptive Cognitive Control Trainer (ACCT)	There are three modules within the game, each training a different aspect of cognitive control (attention, goal management, working memory): a visual search task for attention abilities, a spatial span task for working memory, and a task switching paradigm for goal management abilities. There are also 3 different levels of difficulty associated with each module; advancing to the next level delivers an advanced challenge that enhances the difficulty in performing the given cognitive task. Participants advance to the next level of difficulty following 6 training sessions occurring over 2 weeks, with the total training experience being 6 weeks of training (3 days/week), with each training session lasting 36 minutes (not including self-paced breaks).

Primary Outcome Measures

Name	Time	Method
Mean Change on Adaptive Cognitive Evaluation (ACE) from Baseline at 6 weeks	At Baseline and post intervention at the 6 week mark	ACE is a custom mobile cognitive health assessment battery that presents paradigms typically used in standard cognitive neuroscience laboratories. Here the investigators will assess a measure of (1) Attention (2) Working memory, and (3) Goal management in the ACE software. We will assess response time, accuracy, and response time variability in each case, with faster/more accurate/less variable performance being indicative of improved cognitive control.

Secondary Outcome Measures

Name	Time	Method
Mean Change on Cognitive Failures Questionnaire (CFQ) from Baseline at 6 weeks	At Baseline and post intervention at the 6 week mark	The Cognitive Failures Questionnaire (CFQ) assesses participant distractibility. The CFQ score ranges from 0 to 100, with the lower the overall score is on this measure, the better one is performing with respect to their cognition.
Mean Change on Everyday Cognition Scale (ECog) from Baseline at 6 weeks	At Baseline and post intervention at the 6 week mark	The Everyday Cognition Scale (ECog) measures the ability to perform everyday tasks that demand memory, language, visuospatial abilities, planning, organization, and divided attention. The ECog consists of a global and domain scores for each of the previously described categories, and is scored as follows: 1= better or no change compared to 10 years earlier, 2= questionable/occasionally worse compared to 10 years earlier, 3= consistently a little worse compared to 10 years earlier, 4= consistently much worse compared to 10 years earlier. Thus, the lower the overall score is on this measure at both the global and domain score level, the better one is performing with respect to their cognition.
Mean Change on General health and well-being (SF-36) from Baseline at 6 weeks	At Baseline and post intervention at the 6 week mark	The general health and well-being (SF-36) score assesses participant health. The SF-36 score ranges from 0 to 100. The higher the overall score is on this measure, the better one is performing with respect to their health and well-being.

Trial Locations

Locations (1)

UC San Francisco; 🇺🇸 San Francisco, California, United States