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Clinical Trials/NCT06187077
NCT06187077
Recruiting
Not Applicable

Techquity by FAITH!: A Cluster Randomized Controlled Trial To Assess the Efficacy of a Community-informed, Cardiovascular Health Promotion Mobile Intervention With Digital Health Advocate Support

Mayo Clinic1 site in 1 country200 target enrollmentJuly 11, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Health Equity
Sponsor
Mayo Clinic
Enrollment
200
Locations
1
Primary Endpoint
Physical Activity Score Change (Life's Essential 8 Component)
Status
Recruiting
Last Updated
8 months ago

Overview

Brief Summary

The goal of this clinical trial is to engage African-American churches via an established community-academic partnership (FAITH! Program) to build capacity to promote cardiovascular health and digital health equity in African-American faith communities. There are 3 study aims:

Aim 1: Co-design a culturally tailored digital health equity toolkit with community members

Aim 2: Train a network of Digital Health Advocates (DHAs) in digital health equity and cardiovascular health promotion

Aim 3: Test the impact of a DHA-enhanced mobile health intervention (the FAITH! App) on cardiovascular health and digital health readiness among participants

In Aim 1, participants will attend a series of focus groups to share their input on a digital health equity curriculum that will be condensed into a toolkit.

In Aim 2, DHAs will be trained using this toolkit as well as a community health advocacy curriculum to learn how to promote digital health readiness and cardiovascular health in their communities.

Finally, Aim 3 will be a randomized controlled trial where participants will use the FAITH! App to improve their cardiovascular health. Some participants will have the added support of a DHA, and the control group participants will use the app with no additional support to test whether the DHA support is associated with a more significant improvement in cardiovascular health.

Detailed Description

This study addresses cardiovascular health and digital health disparities faced by African-Americans (AAs). We propose three aims to engage with the AA community and build capacity for a digital literacy and cardiovascular health promotion. Aim 1 will engage AA churches to co-design a culturally relevant digital health equity toolkit through an iterative focus group process. In aim 1, we will recruit 20 AAs to represent their churches and be trained as digital health advocates (DHAs) by completing digital health readiness education (using the toolkit developed in aim 1) and cardiovascular health promotion. This advocacy program will be integrated into an existing mobile health intervention, the FAITH! App, in Aim 3. The impact of the community-informed, mHealth intervention, enhanced with DHA support, on AA adults' cardiovascular health will be assessed in a cluster randomized controlled trial. 150 participants will be be randomized to utilize the FAITH! App alone or with the support of the DHA at their church. Cardiovascular health will be assessed at baseline, approximately 3 months, 6 months, and 12 months post-randomization using the American Heart Association's Life's Essential 8 metric for cardiovascular health.

Registry
clinicaltrials.gov
Start Date
July 11, 2024
End Date
June 30, 2026
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

LaPrincess C. Brewer

Associate Professor of Medicine

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

  • African/American race/ethnicity, age ≥ 18 years, basic Internet navigation skills, active email address
  • Aim 2- Inclusion Criteria: African/American race/ethnicity, age ≥ 18 years, ownership of smartphone (supporting iOS or Android systems), moderate to high digital health literacy (by eHealth literacy scale \[eHEALS\], score ≥26)
  • Aim 3- Inclusion Criteria: African/American race/ethnicity, age ≥ 18 years, ownership of smartphone (supporting iOS or Android systems), low digital health literacy (by eHEALS, score ≤26), basic Internet navigation skills, at least weekly Internet access, active email address, fruit/vegetable intake ≤5 servings/day, no regular physical activity, able to engage in moderate physical activity and willingness to participate in all aspects of the study.

Exclusion Criteria

  • Unable to walk up ≥2 flights of stairs or walk ≥1 city block without assistance or stopping, pregnant (at time of study enrollment), visual/hearing impairment or mental disability that would preclude independent app use.

Outcomes

Primary Outcomes

Physical Activity Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Change from baseline in the total minutes per week that a participant engaged in moderate and vigorous intensity physical activity at immediate post-intervention. Physical activity will be measured by the International Physical Activity Questionnaire (IPAQ).

Blood Pressure Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Average of 3 sitting measurements of systolic and diastolic pressures (mmHg).

Tobacco/Nicotine Exposure Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Changes from baseline in smoking status using the National Health and Nutrition Examination Survey-Smoking-Cigarette Use Questionnaire (NHANES-SMQ), evaluating current and past tobacco use habits.

Fasting Blood Lipids Score Change (non-HDL cholesterol) (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Fingerstick blood collection (mg/dL).

Dietary Quality Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Changes from baseline in healthy diet using the Mediterranean Eating Patterns for Americans (MEPA), a 16-item questionnaire evaluating accordance with a Mediterranean-like diet pattern.

Life's Essential 8 Composite Score change

Time Frame: Baseline, 6-months and 12-months post-randomization

Changes from baseline in Life's Essential 8 score. Life's Essential 8 composite score is determined as a composite of all components by calculating an unweighted average score on a scale of 0 to 100 points. An overall cardiovascular health score (Life's Essential 8 score) will be considered high (80 to 100 points), moderate (50 to 79 points) or low for (0 to 49 points).

Fasting Glucose/Hemoglobin A1c Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Fingerstick blood collection (fasting glucose-mg/dL; Hemoglobin A1c-%).

Body Mass Index (BMI) Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Calculated by weight (kg) and height (m).

Sleep Health Score Change (Life's Essential 8 Component)

Time Frame: Baseline, 6-months and 12-months post-randomization

Changes from baseline in sleep quality (number of hours of sleep nightly) using the Pittsburg Sleep Quality Index (PSQI).

Secondary Outcomes

  • Digital Health Readiness(Baseline, 3 months post-randomization)
  • Social Support - Diet(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Cardio-ankle vascular index (CAVI)(Baseline, 6 months and 12 months post-randomization)
  • Self Regulation - Physical Activity(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Perceived Barriers - Physical Activity(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Self Regulation - Diet(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Perceived Barriers - Diet(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Social Support - Physical Activity(Baseline, 3 months, 6 months, and 12 months post-randomization)
  • Artificial Intelligence (AI)-Electrocardiogram (ECG)(Baseline, 6 months and 12 months post-randomization)

Study Sites (1)

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