Effect of Cognitively Challenging Exergames Using Fully Immersive Virtual Reality in Patients With Parkinson's Disease: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Cognitive dual-task interference (%) in Timed-up & go test
研究概览
简要总结
The study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with Parkinson's disease.
详细描述
It has been reported that dual-task training involving both cognitive and physical functions helps improve walking speed during dual-task performance without increasing the fall risk in patients with Parkinson's disease (PD). Compared with conventional physical therapy, there are studies that dual-task training significantly improved walking speed and stride in PD patients. In addition, a systematic review study has been reported that it helps to improve balance and cognitive function when dual-task training is performed for patients with neurological diseases including Parkinson's disease.
Virtual reality is expected to promote functional recovery in patients with neurological disorders in terms of providing an enriched environment, goal-directed tasks and repetition, and inducing interest and motivation. Therefore, the study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically diagnosed as idiopathic Parkinson's disease
- •Modified Hoehn & Yahr stage 2, 2.5, or 3
排除标准
- •Moderate to severe cognitive dysfunction with Mini-mental State Examination score < 19
- •Severe dyskinesia or severe on-off phenomenon
- •Plan to adjust medication at the time of screening
- •Other brain diseases such as stroke, brain tumor, etc
- •History of seizure
- •Vestibular disease or paroxysmal vertigo
- •Other comorbidities that make it difficult to participate in this study
结局指标
主要结局
Cognitive dual-task interference (%) in Timed-up & go test
时间窗: at study completion, an average of 1 month
Physical dual-task interference (%) in Timed-up & go test
时间窗: at study completion, an average of 1 month
次要结局
- New Freezing of Gait Questionnaire (NFOGQ)(at study completion, an average of 1 month)
- Trail making test(at study completion, an average of 1 month)
- Timed-up & go test (sec): single task(at study completion, an average of 1 month)
- Berg balance scale(at study completion, an average of 1 month)
- Timed-up & go test (sec): cognitive dual-task(at study completion, an average of 1 month)
- Timed-up & go test (sec): physical dual-task(at study completion, an average of 1 month)
- The Unified Parkinson's Disease Rating Scale(at study completion, an average of 1 month)
- Stroop test(at study completion, an average of 1 month)
- Digit span test(at study completion, an average of 1 month)
研究者
Han Gil Seo
Associate Professor
Seoul National University Hospital