TO COMPARE ATRACURIUM AND CISATRACURIUM IN PATIENTS UNDERGOING SURGERIES UNDER GENERAL ANAESTHESIA

Not yet recruiting

• Conditions: Medical and Surgical,; ASA 1 & ASA 2 patients

• Registration Number: CTRI/2021/09/036426
• Lead Sponsor: Dheeraj Gopal Ravindran

Brief Summary

It is a prospective, randomized, double blinded study of comparison of two non depolarizing neuromuscular blocking agents which are Inj. Atracurium and Inj. Cisatracurium in patients undergoing surgeries under general anaesthesia with regards to their potency, onset time of neuromuscular blockade and recovery. Intubating conditions, hemodynamic parameters and side effects if any will also be observed and recorded.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-09-09
• Study Start: 2021-09-16

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA grade I or II fit patients.
• Patients aged between 18 and 60 years of age.
• Patients undergoing surgeries under general anaesthesia.
• Haemodynamically stable patients with all routine investigations within normal limits and without any comorbidities.
• Written informed consent from the concerned patient.

Exclusion Criteria

• Patients who are not willing to participate in the study.
• Patients with ASA grade III and above physical status.
• Patients who are aged less than 18 and more than 60 years of age.
• Patients who are posted for emergency procedures.
• Patients with known allergy to the study drugs.
• Patients with difficult intubation.
• Patients who are obese.
• Patients who have psychiatric, neurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. To compare onset time for intubation.	Time taken from administration of study drug to intubation in seconds and the duration of neuromuscular blockade in minutes
2. To observe intubating conditions.	Time taken from administration of study drug to intubation in seconds and the duration of neuromuscular blockade in minutes
3. To compare duration of neuromuscular blockade.	Time taken from administration of study drug to intubation in seconds and the duration of neuromuscular blockade in minutes

Secondary Outcome Measures

Name	Time	Method
1. To observe hemodynamic effects of both drugs.	2. To observe any side effects.

Trial Locations

Locations (1)

Hightech OT complex, 5th floor, Hightech building; 🇮🇳 Pune, MAHARASHTRA, India

Hightech OT complex, 5th floor, Hightech building

🇮🇳Pune, MAHARASHTRA, India

Dheeraj Gopal Ravindran

Principal investigator

9562372037

93dheeraj@gmail.com