The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease

Withdrawn

• Conditions: Renal Insufficiency, Chronic; Chronic Kidney Diseases

• Registration Number: NCT03397550
• Lead Sponsor: Peking University First Hospital

Brief Summary

The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-12-13
• Study First Submitted QC: 2018-01-10
• Study First Posted: 2018-01-12
• Study Start: 2022-06-18
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-08
• Last Update Posted: 2022-10-12
• Primary Completion: 2022-12-01
• Study Completion: 2023-05-01

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• stage 3-5 CKD patients
• clinical stable

Exclusion Criteria

• renal replacement therapy
• cancer
• systemic infection
• Alzheimer's disease
• acute cardiovascular events, active hepatitis
• all other study-obstructive conditions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ratings of taste sensitivity assessed by the ISO method of investigating sensitivity of taste（ISO 3972:1991）	up to 12 weeks after intervention	Taste sensitivity is measured by five taste solutions（salty、sour、bitter、sweet、umami). Every taste solution contains 8 different concentration. Detection , recognition and difference thresholds will be measured .Their definitions are as bellow.; Detection threshold：minimum value of sensory stimulus needed to give rise to a sensation. The sensation need not be identified.; Recognition threshold：minimum value of a sensory stimulus permitting identification of the sensation perceived.; Difference threshold：value of the smallest perceptible difference in the physical intensity of a stimulus.

Trial Locations

Locations (1)

Peking University First Hospital; 🇨🇳 Beijing, China