Cardiovascular Risk Stratification in Patients With Obstructive Sleep Apnea

• Conditions: Obstructive Sleep Apnea; Obesity

• Registration Number: NCT00768625
• Lead Sponsor: Associacao Fundo de Incentivo a Psicofarmcologia

Brief Summary

The purpose of this study is:

1. To determine the frequency of cardiovascular diseases in patients with OSA, obese, overweight, and lean (BMI\<25)

2. To analyze the CPAP treatment over the clinical evolution of OSA patients

3. To determine if OSA is a independent predictor of cardiovascular risk

Detailed Description

Obstructive Sleep Apnea (OSA) is a condition with important cardiovascular repercussions. However, the association between OSA, cardiovascular diseases, and obesity has not been totally clarified. We hypothesized that the cardiovascular consequences of OSA are due to obesity.

Study Timeline

• Study Start: 2005-04
• Status Verified: 2008-10
• Study First Submitted: 2008-10-07
• Study First Submitted QC: 2008-10-07
• Last Update Submitted: 2008-10-07
• Study First Posted: 2008-10-08
• Last Update Posted: 2008-10-08
• Primary Completion: 2011-03
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• Men and women with OSA (apnea-hypopnea index higher than 5 events/hour)

Exclusion Criteria

• Body mass index higher than 40

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardiovascular events	five years

Trial Locations

Locations (1)

Instituto do Sono/AFIP; 🇧🇷 Sao Paulo, Brazil